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Submit ReviewFuranone C-30
Description: Quorum sensing inhibitor; antibacterial
Chemical Name: (5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone
Purity: ≥98%
Biological Activity for Furanone C-30
Furanone C-30 is a synthetic furanone bacterial quorum sensing inhibitor. Inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Also inhibits bacterial quorum sensing in vivo and promotes bacterial clearance in a mouse pulmonary infection model.
Technical Data for Furanone C-30
| M. Wt | 253.88 |
| Formula | C5H2Br2O2 |
| Storage | Store at -20°C |
| Purity | ≥98% |
| CAS Number | 247167-54-0 |
| PubChem ID | 67228456 |
| InChI Key | DPGLBHQUHFJRJS-UHFFFAOYSA-N |
| Smiles | Br/C=C1OC(C=C\1Br)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Furanone C-30
References for Furanone C-30
References are publications that support the biological activity of the product.
Hentzer et al (2003) Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22 3803 PMID: 12881415
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Keywords: Furanone C-30, Furanone C-30 supplier, quorum, sensing, sensors, Gram-negative, signaling, signalling, inhibits, inhibitors, antibacterial, Antibiotics, 6546, Tocris Bioscience
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