Wnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.
(Modifications: Met-1 = N-Formyl)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in PBS (pH 7.4)|
References are publications that support the biological activity of the product.
Säfholm et al (2008) The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin.Cancer Res. 14 6556 PMID: 18927296
Säfholm et al (2006) A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J.Biol.Chem. 281 2740 PMID: 16330545
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Keywords: Foxy 5, Foxy 5 supplier, Foxy5, wnt5a, peptide, mimetic, Other, Wnt, Signaling, 5461, Tocris Bioscience
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