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Biological Activity for Flutamide
Flutamide is a non-steroidal antiandrogen; competitive antagonist of the androgen receptor. Blocks the biological activity of testosterone (Cat. No. 2822) in vivo.
Compound Libraries for Flutamide
Technical Data for Flutamide
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Flutamide
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Flutamide
The following data is based on the product molecular weight 276.21. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.62 mL||18.1 mL||36.2 mL|
|5 mM||0.72 mL||3.62 mL||7.24 mL|
|10 mM||0.36 mL||1.81 mL||3.62 mL|
|50 mM||0.07 mL||0.36 mL||0.72 mL|
References for Flutamide
References are publications that support the biological activity of the product.
Sufrin and Coffey (1976) Flutamide. Mechanism of action of a new nonsteroidal antiandrogen. Invest.Urol. 13 429 PMID: 1270239
Butcher et al (2007) Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells. Cancer Res. 67 85 PMID: 17210686
Foster et al (2011) Drug safety is a barrier to the discovery and development of new androgen receptor antagonists. Prostate 71 480 PMID: 20878947
If you know of a relevant reference for Flutamide, please let us know.
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Keywords: Flutamide, Flutamide supplier, androgen, receptors, antagonists, antiandrogen, nonsteroidal, SCH13521, chemotherapeutics, SCH, 13521, Androgen, Receptor, 4094, Tocris Bioscience
Citations for Flutamide
Citations are publications that use Tocris products.
Currently there are no citations for Flutamide. Do you know of a great paper that uses Flutamide from Tocris? Please let us know.
Reviews for Flutamide
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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