Fluconazole

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Cat.No. 3764 - Fluconazole | C13H12F2N6O | CAS No. 86386-73-4
Description: Triazole antifungal agent
Alternative Names: UK 49858
Chemical Name: 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
Datasheet
Citations
Literature

Biological Activity

Triazole antifungal agent. Effective against Candida strains in vitro and in vivo.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

M. Wt 306.27
Formula C13H12F2N6O
Storage Store at +4°C
CAS Number 86386-73-4
PubChem ID 3365
InChI Key RFHAOTPXVQNOHP-UHFFFAOYSA-N
Smiles OC(CN2N=CN=C2)(CN3N=CN=C3)C1=C(F)C=C(F)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.63 100
ethanol 30.63 100

Preparing Stock Solutions

The following data is based on the product molecular weight 306.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.27 mL 16.33 mL 32.65 mL
5 mM 0.65 mL 3.27 mL 6.53 mL
10 mM 0.33 mL 1.63 mL 3.27 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Saag and Dismukes (1988) Azole antifungal agents: emphasis on new triazoles. Antimicrob.Agents Chemother. 32 1 PMID: 2831809


If you know of a relevant reference for Fluconazole, please let us know.

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Keywords: antifungal triazole UK49858 Pfizer UK 49858 Miscellaneous Compounds

Citations for Fluconazole

Citations are publications that use Tocris products.

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Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for Fluconazole

Protocols

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