Fenofibrate

Pricing Availability   Qty
Description: PPARα agonist
Chemical Name: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester
Purity: ≥99% (HPLC)
Datasheet
Citations (5)
Reviews
Literature (1)

Biological Activity for Fenofibrate

Fenofibrate is a PPARα agonist; hypolipidemic. Attenuates insulin resistance and increases high-density lipoprotein-cholesterol in db/db mice.

Compound Libraries for Fenofibrate

Fenofibrate is also offered as part of the Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Fenofibrate

M. Wt 360.83
Formula C20H21ClO4
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 49562-28-9
PubChem ID 3339
InChI Key YMTINGFKWWXKFG-UHFFFAOYSA-N
Smiles CC(C)OC(C(C)(C)OC(C=C2)=CC=C2C(C1=CC=C(Cl)C=C1)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Fenofibrate

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.08 100
ethanol 36.08 100

Preparing Stock Solutions for Fenofibrate

The following data is based on the product molecular weight 360.83. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.77 mL 13.86 mL 27.71 mL
5 mM 0.55 mL 2.77 mL 5.54 mL
10 mM 0.28 mL 1.39 mL 2.77 mL
50 mM 0.06 mL 0.28 mL 0.55 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets for Fenofibrate

Certificate of Analysis / Product Datasheet
Select another batch:

References for Fenofibrate

References are publications that support the biological activity of the product.

Mandard et al (2004) The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofi. treatment. J.Biol.Chem. 279 34411 PMID: 15190076

Park et al (2006) PPARα agonist fenofi. improves diabetic nephropathy in db/db mice. Kidney Int. 69 1511 PMID: 16672921

Balakumar et al (2011) Pleiotropic actions of fenofi. on the heart. Pharmacol.Res. 63 8 PMID: 21093591


If you know of a relevant reference for Fenofibrate, please let us know.

View Related Products by Target

View Related Products by Product Action

View all PPARα Agonists

Keywords: Fenofibrate, Fenofibrate supplier, peroxisome, proliferator-activated, receptors, pparalpha, PPARa, PPARα, agonists, PPARalpha, Receptors, 4113, Tocris Bioscience

Reviews for Fenofibrate

There are currently no reviews for this product. Be the first to review Fenofibrate and earn rewards!

Have you used Fenofibrate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer Research Product Guide

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis