You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC50 ~ 20 μM). Has similar, but not identical, action to brefeldin A (Cat. No. 1231).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|ethanol||6.83||25 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 273.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.66 mL||18.3 mL||36.6 mL|
|5 mM||0.73 mL||3.66 mL||7.32 mL|
|10 mM||0.37 mL||1.83 mL||3.66 mL|
|50 mM||0.07 mL||0.37 mL||0.73 mL|
References are publications that support the biological activity of the product.
Feng et al (2003) Exo1: A new chemical inhibitor of the exocytic pathway. Proc.Natl.Acad.Sci.U.S.A. 100 6469 PMID: 12738886
If you know of a relevant reference for Exo1, please let us know.
Keywords: Exo1, Exo1 supplier, inhibitors, inhibits, Golgi-ER, traffic, blocks, exocytosis, Golgi, ADP-ribosylation, factor, ARF1, GTPase, Translocation,, Exocytosis, &, Endocytosis, 1850, Tocris Bioscience
2 Citations for Exo1
Citations are publications that use Tocris products. Selected citations for Exo1 include:
Eppler et al (2017) Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion. PLoS One 12 e0172443 PMID: 28273099
Greene et al (2017) XE991 and Linopirdine are state-dependent inhibitors for Kv7/KCNQ channels that favor activated single subunits. J.Pharmacol.Exp.Ther. 362 177 PMID: 28483800
Do you know of a great paper that uses Exo1 from Tocris? Please let us know.
Reviews for Exo1
There are currently no reviews for this product. Be the first to review Exo1 and earn rewards!
Have you used Exo1?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide [Spring/Summer 2019]
Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells