Potent natural tachykinin receptor ligand (pD2 values are 9.21, 8.22 and 7.11 for guinea pig NK1, rabbit NK2 and rat NK3 receptors respectively).
(Modifications: X = Glp, Met-11 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 0.20 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1188.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.84 mL||4.21 mL||8.41 mL|
|5 mM||0.17 mL||0.84 mL||1.68 mL|
|10 mM||0.08 mL||0.42 mL||0.84 mL|
|50 mM||0.02 mL||0.08 mL||0.17 mL|
References are publications that support the products' biological activity.
Regoli et al (1989) Receptors for substance P and related neurokinins. Pharmacology 38 1 PMID: 2542998
Severini et al (2002) The tachykinin peptide family. Pharmacol.Rev. 54 285 PMID: 12037144
Sturmer et al (1964) Synthetic peptides related to eledoisin. Experientia 20 303 PMID: 5855848
If you know of a relevant reference for Eledoisin, please let us know.
Keywords: Eledoisin, supplier, Potent, tachykinin, receptor, ligands, Tachykinin, Non-Selective, Neurokinin, Receptors, Other, Tachykinin, Other, Tachykinin, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.