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Cat.No. 1914 - Eledoisin | Glp-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 | CAS No. 69-25-0
Description: Potent tachykinin receptor ligand

Biological Activity

Potent natural tachykinin receptor ligand (pD2 values are 9.21, 8.22 and 7.11 for guinea pig NK1, rabbit NK2 and rat NK3 receptors respectively).

Technical Data

M. Wt 1188.4
Formula C54H85N13O15S

(Modifications: X = Glp, Met-11 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 69-25-0
PubChem ID 10328936
Smiles [H]N1[C@@H](CCC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 0.20 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1188.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.84 mL 4.21 mL 8.41 mL
5 mM 0.17 mL 0.84 mL 1.68 mL
10 mM 0.08 mL 0.42 mL 0.84 mL
50 mM 0.02 mL 0.08 mL 0.17 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Regoli et al (1989) Receptors for substance P and related neurokinins. Pharmacology 38 1 PMID: 2542998

Severini et al (2002) The tachykinin peptide family. Pharmacol.Rev. 54 285 PMID: 12037144

Sturmer et al (1964) Synthetic peptides related to eledoisin. Experientia 20 303 PMID: 5855848

If you know of a relevant reference for Eledoisin, please let us know.

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Keywords: Potent tachykinin receptor ligands Tachykinin Non-Selective Neurokinin Receptors Other Tachykinin Peptide

Citations for Eledoisin

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