Biological Activity
Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).
Technical Data
M. Wt | 1666.98 |
Formula | C76H127N23O19 |
Sequence |
XVXEIQLXHQRAKY (Modifications: X-1, X-3 = Aib, X-8 = Nle, Tyr-14 = C-terminal amide) |
Storage | Store at -20°C |
CAS Number | 943519-33-3 |
PubChem ID | 44584922 |
InChI Key | PNJXWIJKATVXEY-FAQCDESUSA-N |
Smiles | [H]N([C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O)C(=O)C(C)(C)NC(=O)[C@@H](N([H])C(=O)C(C)(C)N)C(C)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solubility | Soluble to 1 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 1666.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 0.6 mL | 3 mL | 6 mL |
5 mM | 0.12 mL | 0.6 mL | 1.2 mL |
10 mM | 0.06 mL | 0.3 mL | 0.6 mL |
50 mM | 0.01 mL | 0.06 mL | 0.12 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Carter et al (2007) Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe. Proc.Natl.Acad.Sci.U.S.A. 104 6846 PMID: 17428923
If you know of a relevant reference for DPC AJ1951, please let us know.
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Keywords: DPC AJ1951, supplier, DPCAJ1951, potent, 14, amino, acid, peptide, agonists, PTH, receptors, Parathyroid, Hormone, Receptors, Parathyroid, Hormone, Receptors, Tocris Bioscience
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