(±)-Palmitoylcarnitine chloride

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Cat.No. 0609 - (±)-Palmitoylcarnitine chloride | C23H46ClNO4 | CAS No. 6865-14-1
Description: Intermediate in fatty acid oxidation
Datasheet
Citations
Reviews
Literature (1)

Biological Activity

Intermediate in mitochondrial fatty acid oxidation. Has a wide range of biological actions including the inhibition of protein kinase C and cell membrane disruption.

Technical Data

M. Wt 436.07
Formula C23H46ClNO4
Storage Desiccate at RT
CAS Number 6865-14-1
PubChem ID 363417
InChI Key GAMKNLFIHBMGQT-UHFFFAOYSA-N
Smiles [Cl-].CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 10.9 25

Preparing Stock Solutions

The following data is based on the product molecular weight 436.07. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 9.17 mL 45.86 mL 91.73 mL
1.25 mM 1.83 mL 9.17 mL 18.35 mL
2.5 mM 0.92 mL 4.59 mL 9.17 mL
12.5 mM 0.18 mL 0.92 mL 1.83 mL

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References

References are publications that support the biological activity of the product.

Criddle et al (1990) The effects of novel vasodilator long chain acyl carnitine esters in the isolated perfused heart of the rat. Br.J.Pharmacol. 99 477 PMID: 1691947

Dainty et al (1990) Interactions of palmitoyl carnitine with the endothelium in rat aorta. Br.J.Pharmacol. 100 241 PMID: 1696151

Nakadate and Blumberg (1987) Modulation by palmitoylcarnitine of protein kinase C activation. Cancer Res. 47 6537 PMID: 3479247

Requero et al (1995) The membrane-perturbing properties of palmitoyl-coenzyme A and palmitoylcarnitine. A comparative study. Biochemistry 34 10400 PMID: 7654694


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Keywords: (±)-Palmitoylcarnitine chloride, (±)-Palmitoylcarnitine chloride supplier, Protein, kinase, C, inhibitors, inhibits, PKC, Kinases, fatty, acid, oxidation, Kinase, Other, Lipid, Metabolism, 0609, Tocris Bioscience

Citations for (±)-Palmitoylcarnitine chloride

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Literature in this Area

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