(±)-AC 7954 hydrochloride
Highly selective, non-peptide urotensin-II (UT) receptor agonist that displays potent activity at human and rat UT receptors (pEC50 values are 6.5 and 6.7 respectively).
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 366.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.73 mL||13.65 mL||27.3 mL|
|5 mM||0.55 mL||2.73 mL||5.46 mL|
|10 mM||0.27 mL||1.37 mL||2.73 mL|
|50 mM||0.05 mL||0.27 mL||0.55 mL|
References are publications that support the biological activity of the product.
Croston et al (2002) Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954). J.Med.Chem. 45 4950 PMID: 12408704
Lavecchia et al (2005) Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists. J.Med.Chem. 48 2480 PMID: 15801838
Lehmann et al (2006) Novel potent and efficacious nonpeptidic urotensin II receptor agonists. J.Med.Chem. 49 2232 PMID: 16570919
If you know of a relevant reference for (±)-AC 7954 hydrochloride, please let us know.
View Related Products by Product Action
Keywords: (±)-AC 7954 hydrochloride, (±)-AC 7954 hydrochloride supplier, Non-peptide, UT, receptor, agonists, Receptors, Urotensin-II, (±)-AC7954, hydrochloride, 2484, Tocris Bioscience
Citations for (±)-AC 7954 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for (±)-AC 7954 hydrochloride. Do you know of a great paper that uses (±)-AC 7954 hydrochloride from Tocris? Please let us know.
Reviews for (±)-AC 7954 hydrochloride
There are currently no reviews for this product. Be the first to review (±)-AC 7954 hydrochloride and earn rewards!
Have you used (±)-AC 7954 hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.