(±)-3-(3-Nitrobenzoyl)alanine hydrochloride

Discontinued Product

(±)-3-(3-Nitrobenzoyl)alanine hydrochloride (Cat. No. 0799) has been withdrawn from sale for commercial reasons.
Cat.No. 0799 - (±)-3-(3-Nitrobenzoyl)alanine hydrochloride
Description: Kynurenine-3-hydroxylase inhibitor
Datasheet
Citations
Reviews
Literature

Biological Activity

The first potent and selective inhibitor of kynurenine-3-hydroxylase. Increases the concentration of kynurenic acid in vivo.

Technical Data

M. Wt 238.2
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Safety Datasheet

References

References are publications that support the biological activity of the product.

Carpendo et al (1994) Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities. Neuroscience 61 237 PMID: 7969905

Chiarugi and Moroni (1999) Quinolinic acid formation in immune-activated mice: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(-3-nitrophenyl)thiazol-2yl]-benzenesulfonamide. Neuropharmacology 38 1225 PMID: 10462134

Pellicciari et al (1994) Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase. J.Med.Chem. 37 647 PMID: 8126705

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Keywords: (±)-3-(3-Nitrobenzoyl)alanine hydrochloride, (±)-3-(3-Nitrobenzoyl)alanine hydrochloride supplier, Non-selective, Ionotropic, Glutamate, 0799, Tocris Bioscience

Citations for (±)-3-(3-Nitrobenzoyl)alanine hydrochloride

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Literature in this Area

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