Dequalinium dichloride

Cat. No. 0674 Datasheet / COA / SDS

Discontinued Product

Unfortunately Dequalinium dichloride (Cat. No. 0674) has been withdrawn from sale for commercial reasons.
Cat.No. 0674 - Dequalinium dichloride | C30H40Cl2N4 | CAS No. 522-51-0
Description: K+ channel blocker (SKCa)
Chemical Name: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride

Biological Activity

A potent and selective non-peptide blocker of the apamin-sensitive small conductance Ca2+-activated K+ channel (IC50 = 1.1 mM).

Technical Data

M. Wt 527.58
Formula C30H40Cl2N4
Storage Store at RT
CAS Number 522-51-0
Smiles NC2=CC(C)=[N+](CCCCCC)C1=CC=CC=C12.[Cl-].[Cl-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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Safety Datasheet


References are publications that support the products' biological activity.

Dunn (1994) Dequalinium, a selective blocker of the slow afterhyperpolarization in rat sympathetic neurones in culture. Eur.J Pharmacol. 252 189 PMID: 8157060

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Keywords: Dequalinium dichloride, supplier, K+, channel, blockers, SKCa, Potassium, Channels, BKCa, Maxi-K, sAHP, ca2+-activated, ca2+-dependent, Ca2+-Activated, Potassium, Channels, Ca2+-Activated, Potassium, Channels, Tocris Bioscience

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