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Submit ReviewDequalinium dichloride
Discontinued Product
Dequalinium dichloride (Cat. No. 0674) has been withdrawn from sale for commercial reasons.
Description: K+ channel blocker (SKCa)
Chemical Name: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride
Biological Activity for Dequalinium dichloride
A potent and selective non-peptide blocker of the apamin-sensitive small conductance Ca2+-activated K+ channel (IC50 = 1.1 mM).
Technical Data for Dequalinium dichloride
| M. Wt | 527.58 |
| Formula | C30H40Cl2N4 |
| Storage | Store at RT |
| CAS Number | 522-51-0 |
| Smiles | NC2=CC(C)=[N+](CCCCCC)C1=CC=CC=C12.[Cl-].[Cl-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Dequalinium dichloride
Certificate of Analysis is currently unavailable on-line.
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References for Dequalinium dichloride
References are publications that support the biological activity of the product.
Dunn (1994) Dequalinium, a selective blocker of the slow afterhyperpolarization in rat sympathetic neurones in culture. Eur.J Pharmacol. 252 189 PMID: 8157060
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Keywords: Dequalinium dichloride, Dequalinium dichloride supplier, K+, channel, blockers, SKCa, Potassium, Channels, BKCa, Maxi-K, sAHP, ca2+-activated, ca2+-dependent, Ca2+-Activated, 0674, Tocris Bioscience
Citations for Dequalinium dichloride
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Currently there are no citations for Dequalinium dichloride.
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