Dequalinium dichloride

Discontinued Product

Dequalinium dichloride (Cat. No. 0674) has been withdrawn from sale for commercial reasons.
Description: K+ channel blocker (SKCa)
Chemical Name: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride
Literature (2)

Biological Activity for Dequalinium dichloride

A potent and selective non-peptide blocker of the apamin-sensitive small conductance Ca2+-activated K+ channel (IC50 = 1.1 mM).

Technical Data for Dequalinium dichloride

M. Wt 527.58
Formula C30H40Cl2N4
Storage Store at RT
CAS Number 522-51-0
Smiles NC2=CC(C)=[N+](CCCCCC)C1=CC=CC=C12.[Cl-].[Cl-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Dequalinium dichloride

Certificate of Analysis is currently unavailable on-line.
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References for Dequalinium dichloride

References are publications that support the biological activity of the product.

Dunn (1994) Dequalinium, a selective blocker of the slow afterhyperpolarization in rat sympathetic neurones in culture. Eur.J Pharmacol. 252 189 PMID: 8157060

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Keywords: Dequalinium dichloride, Dequalinium dichloride supplier, K+, channel, blockers, SKCa, Potassium, Channels, BKCa, Maxi-K, sAHP, ca2+-activated, ca2+-dependent, Ca2+-Activated, 0674, Tocris Bioscience

Citations for Dequalinium dichloride

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