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Inhibitor of the plasma membrane monoamine transporter (PMAT) (Ki = 0.10 μM).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 454.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||22.01 mL||110.05 mL||220.09 mL|
|0.5 mM||4.4 mL||22.01 mL||44.02 mL|
|1 mM||2.2 mL||11 mL||22.01 mL|
|5 mM||0.44 mL||2.2 mL||4.4 mL|
References are publications that support the biological activity of the product.
Engel and Wang (2005) Interaction of organic cations with a newly identified plasma membrane monoamine transporter. Mol.Pharmacol. 68 1397 PMID: 16099839
Xia et al (2009) Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity. Am.J.Physiol.Renal Physiol. 296 F1307 PMID: 19357181
If you know of a relevant reference for Decynium 22, please let us know.
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Keywords: Decynium 22, Decynium 22 supplier, Decynium22, PMAT, plasma, membrane, monoamine, transporters, inhibitors, inhibits, Nucleoside, Transporters, 4722, Tocris Bioscience
1 Citation for Decynium 22
Citations are publications that use Tocris products. Selected citations for Decynium 22 include:
He et al (2017) Downregulation of miR-7116-5p in microglia by MPP+ sensitizes TNF-α production to induce dopaminergic neuron damage. Glia 65 1251 PMID: 28543680
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Literature in this Area
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