You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.
(Modifications: X = Glp, Phe-12 = D-Phe, Leu-14 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 10 mg/ml in water|
References are publications that support the biological activity of the product.
Heinz-Erian et al (1987) [d-Phe12]bombesin analogues: a new class of bombesin receptor antagonists. Am.J.Physiol. 252 G439 PMID: 2435173
Merali et al (1988) (d-Phe12) bombesin and substance P analogues function as central bombesin receptor antagonists. Synapse 2 282 PMID: 2463692
Flynn (1997) Bombesin receptor antagonists block the effects of exogenous bombesin but not of nutrients on food intake. Physiol.Behav. 62 791 PMID: 9284499
If you know of a relevant reference for [D-Phe12,Leu14]-Bombesin, please let us know.
View Related Products by Product Action
Keywords: [D-Phe12,Leu14]-Bombesin, [D-Phe12,Leu14]-Bombesin supplier, Bombesin, receptor, antagonists, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, 3422, Tocris Bioscience
Citations for [D-Phe12,Leu14]-Bombesin
Citations are publications that use Tocris products.
Currently there are no citations for [D-Phe12,Leu14]-Bombesin. Do you know of a great paper that uses [D-Phe12,Leu14]-Bombesin from Tocris? Please let us know.
Reviews for [D-Phe12,Leu14]-Bombesin
There are currently no reviews for this product. Be the first to review [D-Phe12,Leu14]-Bombesin and earn rewards!
Have you used [D-Phe12,Leu14]-Bombesin?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.