D-myo-Inositol 1,4,5-trisphosphate, sodium salt

Discontinued Product

Cat.No. 1335 - D-myo-Inositol 1,4,5-trisphosphate, sodium salt | CAS No. 108340-81-4
Description: Ca2+ mobilising second messenger
Chemical Name: D-myo-inositol,1,4,5-tris(dihydrogenphosphate)hexasodium salt
Purity: ≥99% (HPLC)

Biological Activity

Important second messenger involved in Ca2+ mobilisation from intracellular stores (EC50 = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.

Technical Data

M. Wt 551.99
Storage Desiccate at -20°C
Purity ≥99% (HPLC)
CAS Number 108340-81-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 551.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.81 mL 9.06 mL 18.12 mL
5 mM 0.36 mL 1.81 mL 3.62 mL
10 mM 0.18 mL 0.91 mL 1.81 mL
50 mM 0.04 mL 0.18 mL 0.36 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Joseph et al (1984) myo-Inositol 1,4,5-trisphosphate. J.Biol.Chem. 259 3077 PMID: 6607924

Murphy et al (1996) Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors. Mol.Pharmacol. 50 1223 PMID: 8913354

Wilcox et al (1998) New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. TiPS 19 467 PMID: 9850611

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Keywords: D-myo-Inositol 1,4,5-trisphosphate, sodium salt, supplier, Inositol, Lipids, Inositol, Lipids, Tocris Bioscience

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