D-myo-Inositol 1,4,5-trisphosphate, sodium salt

Description: Ca2+ mobilising second messenger
Chemical Name: D-myo-inositol,1,4,5-tris(dihydrogenphosphate)hexasodium salt
Purity: ≥99% (HPLC)

Biological Activity

Important second messenger involved in Ca2+ mobilisation from intracellular stores (EC50 = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.

Technical Data

M. Wt 551.99
Storage Desiccate at -20°C
Purity ≥99% (HPLC)
CAS Number 108340-81-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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References are publications that support the biological activity of the product.

Joseph et al (1984) myo-Inositol 1,4,5-trisphosphate. J.Biol.Chem. 259 3077 PMID: 6607924

Murphy et al (1996) Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors. Mol.Pharmacol. 50 1223 PMID: 8913354

Wilcox et al (1998) New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. TiPS 19 467 PMID: 9850611

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Keywords: D-myo-Inositol 1,4,5-trisphosphate, sodium salt, D-myo-Inositol 1,4,5-trisphosphate, sodium salt supplier, Inositol, Lipids, 1335, Tocris Bioscience

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