D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt

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Cat.No. 1482 - D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt | C6H9O15P3.K6 | CAS No. 103476-24-0
Description: Ca2+ mobilizing second messenger
Datasheet
Citations
Literature

Biological Activity

Important second messenger involved in Ca2+ mobilization from intracellular stores (EC50 = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.

Technical Data

M. Wt 648.64
Formula C6H9O15P3.K6
Storage Store at -20°C
CAS Number 103476-24-0
PubChem ID 16219525
InChI Key DVOPWCOAGWTTEN-PPKFVSOLSA-H
Smiles [K+].[K+].[K+].[K+].[K+].[K+].O[C@@H]1[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](O)[C@@H]1OP([O-])([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in water

Preparing Stock Solutions

The following data is based on the product molecular weight 648.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.54 mL 7.71 mL 15.42 mL
5 mM 0.31 mL 1.54 mL 3.08 mL
10 mM 0.15 mL 0.77 mL 1.54 mL
50 mM 0.03 mL 0.15 mL 0.31 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Joseph et al (1984) myo-Inositol 1,4,5-trisphosphate. J.Biol.Chem. 259 3077 PMID: 6607924

Murphy et al (1996) Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors. Mol.Pharmacol. 50 1223 PMID: 8913354

Wilcox et al (1998) New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. TiPS 19 467 PMID: 9850611


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Citations for D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt

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