D-Glutamic acid

Pricing Availability Delivery Time Qty
Cat.No. 0217 - D-Glutamic acid | C5H9NO4 | CAS No. 6893-26-1
Description: Endogenous, non-selective agonist. Less active enantiomer
Chemical Name: (R)-1-Aminopropane-1,3-dicarboxylic acid
Datasheet
Citations
Literature

Biological Activity

Excitatory amino acid acting at NMDA receptors; less active than the L-isomer, L-glutamic acid (Cat. No. 0218).

Technical Data

M. Wt 147.13
Formula C5H9NO4
Storage Store at RT
CAS Number 6893-26-1
PubChem ID 23327
InChI Key WHUUTDBJXJRKMK-GSVOUGTGSA-N
Smiles N[C@@]([H])([C@](O)=O)CCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in 1eq. NaOH

Preparing Stock Solutions

The following data is based on the product molecular weight 147.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.8 mL 33.98 mL 67.97 mL
5 mM 1.36 mL 6.8 mL 13.59 mL
10 mM 0.68 mL 3.4 mL 6.8 mL
50 mM 0.14 mL 0.68 mL 1.36 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Olverman et al (1988) Structure/activity relations of N-methyl-D-aspartate receptor ligands as studied by their inhibition of [3H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 26 17 PMID: 2901691

Watkins (1986) Twenty five years of excitatory amino acid research. Excitatory Amino Acids. Eds. Roberts et al. Macmil p1-39 PMID:


If you know of a relevant reference for D-Glutamic acid, please let us know.

View Related Products by Product Action

View all Non-selective Ionotropic Glutamate Agonists

Keywords: D-Glutamic acid, supplier, Endogenous, non-selective, agonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, Ionotropic, Glutamate, Non-selective, mGlu, Non-selective, Ionotropic, Glutamate, Tocris Bioscience

Citations for D-Glutamic acid

Citations are publications that use Tocris products.

Currently there are no citations for D-Glutamic acid. Do you know of a great paper that uses D-Glutamic acid from Tocris? If so please let us know.

D-Glutamic acid Reviews

Average Rating:

(Based on 0 Reviews)


1 Star
0%
2 Star
0%
3 Star
0%
4 Star
0%
5 Star
0%

Have you used D-Glutamic acid?

Submit a review and receive a $25US/€18/£15/$25CAN Amazon gift card if you include an image -$10US/€7/£6/$10CAN Amazon gift card for reviews without an image. Limited to verified customers in USA, Canada and Europe.


Literature in this Area

Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Pain

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

Parkinson's

Parkinson's Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.