D-Glutamic acid

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Cat.No. 0217 - D-Glutamic acid | C5H9NO4 | CAS No. 6893-26-1
Description: Endogenous, non-selective agonist. Less active enantiomer
Chemical Name: (R)-1-Aminopropane-1,3-dicarboxylic acid

Biological Activity

Excitatory amino acid acting at NMDA receptors; less active than the L-isomer.

L-isomer also available.

Technical Data

M. Wt 147.13
Formula C5H9NO4
Storage Store at RT
CAS Number 6893-26-1
PubChem ID 23327
Smiles N[C@@]([H])([C@](O)=O)CCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in 1eq. NaOH

Preparing Stock Solutions

The following data is based on the product molecular weight 147.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.8 mL 33.98 mL 67.97 mL
5 mM 1.36 mL 6.8 mL 13.59 mL
10 mM 0.68 mL 3.4 mL 6.8 mL
50 mM 0.14 mL 0.68 mL 1.36 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Olverman et al (1988) Structure/activity relations of N-methyl-D-aspartate receptor ligands as studied by their inhibition of [3H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 26 17 PMID: 2901691

Watkins (1986) Twenty five years of excitatory amino acid research. Excitatory Amino Acids. Eds. Roberts et al. Macmil p1-39 PMID:

If you know of a relevant reference for D-Glutamic acid, please let us know.

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