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Biological Activity for CYM 9484
CYM 9484 is a potent neuropeptide Y (NPY) Y2 receptor antagonist (IC50 = 19 nM).
Sold under license from The Scripps Research Institute
Technical Data for CYM 9484
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for CYM 9484
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for CYM 9484
The following data is based on the product molecular weight 509.63. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.96 mL||9.81 mL||19.62 mL|
|5 mM||0.39 mL||1.96 mL||3.92 mL|
|10 mM||0.2 mL||0.98 mL||1.96 mL|
|50 mM||0.04 mL||0.2 mL||0.39 mL|
References for CYM 9484
References are publications that support the biological activity of the product.
Mittapalli et al (2012) Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg.Med.Chem.Lett. 22 3916 PMID: 22607676
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Keywords: CYM 9484, CYM 9484 supplier, CYM9484, neuropeptides, Y, NPY, Y2, antagonists, potent, Receptors, 4606, Tocris Bioscience
1 Citation for CYM 9484
Citations are publications that use Tocris products. Selected citations for CYM 9484 include:
Jaroslaw et al (2020) Inflammation changes the expression of neuropeptide Y receptors in the pig myometrium and their role in the uterine contractility. PLoS One 15 e0236044 PMID: 32649683
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.