CYM 9484

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Cat.No. 4606 - CYM 9484 | C27H31N3O3S2 | CAS No. 1383478-94-1
Description: Potent NPY Y2 receptor antagonist
Chemical Name: N-[4-[(Dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent neuropeptide Y (NPY) Y2 receptor antagonist (IC50 = 19 nM).

Licensing Information

Sold under license from The Scripps Research Institute

Technical Data

M. Wt 509.63
Formula C27H31N3O3S2
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 1383478-94-1
PubChem ID 66561564
InChI Key VAUKHARIAMDAGF-UHFFFAOYSA-N
Smiles OC(C2=CC=CC=C2)(C3=CC=CC=C3)C1CCN(C(NC4=CC=C(S(=O)(N(C)C)=O)C=C4)=S)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 50.96 100

Preparing Stock Solutions

The following data is based on the product molecular weight 509.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.96 mL 9.81 mL 19.62 mL
5 mM 0.39 mL 1.96 mL 3.92 mL
10 mM 0.2 mL 0.98 mL 1.96 mL
50 mM 0.04 mL 0.2 mL 0.39 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Mittapalli et al (2012) Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg.Med.Chem.Lett. 22 3916 PMID: 22607676


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