Cyanine 5.5, SE

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Cat.No. 7431 - Cyanine 5.5, SE | C45H44N3O16S4.3C6H15NH
Description: Far red fluorescent dye for the labeling of amines; supplied as NHS ester
Alternative Names: Cy5.5, Sulpho-Cyanine 5.5
Chemical Name: Tris(triethylammonium) 3-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-2-((1E,3E,5Z)-5-(3-ethyl-1,1-dimethyl-6,8-disulfonato-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-6,8-disulfonate
Purity: ≥90% (HPLC)
Literature (1)

Biological Activity for Cyanine 5.5, SE

Cyanine 5.5, SE is a far red fluorescent dye for the labeling of amines. Cyanine 5.5, SE is ideal for labeling antibodies, peptides, glycoproteins, and amine-rich proteins. Cyanine 5.5, SE is also suitable for in vivo imaging. Excitation maximum ~675 nm; emission maximum ~694 nm.

Optical Data for Cyanine 5.5, SE

Emission Color Far Red
λabs 675 nm
λem 694 nm
Extinction Coefficient (ε) 190000 M-1cm-1
Quantum Yield (φ) 0.28
Reactive Group NHS ester
Application labeling antibodies, peptides, glycoproteins, and amine-rich proteins - suitable for in vivo imaging
Alternative For Alexa Fluor® 680, and DyLight 680

Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company.

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Technical Data for Cyanine 5.5, SE

M. Wt 1317.7
Formula C45H44N3O16S4.3C6H15NH
Storage Store at -20°C
Purity ≥90% (HPLC)
Smiles CCN1C2=C(C(C)(/C1=C/C=C/C=C/C3=[N+](C4=C(C3(C)C)C5=CC(S([O-])(=O)=O)=CC(S([O-])(=O)=O)=C5C=C4)CCCCCC(ON6C(CCC6=O)=O)=O)C)C7=CC(S([O-])(=O)=O)=CC(S([O-])(=O)=O)=C7C=C2.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Cyanine 5.5, SE

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 10 8

Preparing Stock Solutions for Cyanine 5.5, SE

The following data is based on the product molecular weight 1317.7. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.08 mM 9.49 mL 47.43 mL 94.86 mL
0.4 mM 1.9 mL 9.49 mL 18.97 mL
0.8 mM 0.95 mL 4.74 mL 9.49 mL
4 mM 0.19 mL 0.95 mL 1.9 mL

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Product Datasheets for Cyanine 5.5, SE

References for Cyanine 5.5, SE

References are publications that support the biological activity of the product.

Ma et al (2012) Ultrasmall sub-10 nm near-infrared fluorescent mesoporous silica nanoparticles. J.Am.Chem.Soc. 134 13180 PMID: 22830608

Kim et al (2006) Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging. J.Am.Chem.Soc. 128 3490 PMID: 16536501

Weissleder et al (1999) In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat.Biotechnol 17 375 PMID: 10207887

If you know of a relevant reference for Cyanine 5.5, SE, please let us know.

Keywords: Cyanine 5.5, SE, Cyanine 5.5, SE supplier, Sulpho-Cyanine, 5.5, Cy5.5, far, red, fluorescent, dyes, stains, labeling, labelling, amines, in, vivo, imaging, Cyanine, Dyes, (Cy, Dyes), 7431, Tocris Bioscience

Citations for Cyanine 5.5, SE

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