CV 1808

Pricing Availability   Qty
Description: Non-selective adenosine A2 receptor agonist
Chemical Name: 2-Phenylaminoadenosine
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Reviews

Biological Activity for CV 1808

CV 1808 is an adenosine A2 receptor agonist. Coronary vasodilator, antihypertensive and antipsychotic following systemic administration in vivo.

Technical Data for CV 1808

M. Wt 358.36
Formula C16H18N6O4
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 53296-10-9
PubChem ID 6917803
InChI Key SCNILGOVBBRMBK-SDBHATRESA-N
Smiles O[C@@H]1[C@@H](CO)O[C@@H](N(C=N3)C2=C3C(N)=NC(NC4=CC=CC=C4)=N2)[C@@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CV 1808

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 3.58 10

Preparing Stock Solutions for CV 1808

The following data is based on the product molecular weight 358.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.9 mL 139.52 mL 279.05 mL
0.5 mM 5.58 mL 27.9 mL 55.81 mL
1 mM 2.79 mL 13.95 mL 27.9 mL
5 mM 0.56 mL 2.79 mL 5.58 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets for CV 1808

Certificate of Analysis / Product Datasheet
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References for CV 1808

References are publications that support the biological activity of the product.

Abiru et al (1991) The antihypertensive effect of 2-alkynyladenosines and the selective affinity for adenosine A2 receptors. Eur.J.Pharmacol. 196 69 PMID: 1874281

Martin et al (1993) Adenosine agonists reduce conditioned avoidance responding in the rat. Pharmacol.Biochem.Behav. 45 951 PMID: 8105493

Marumoto et al (1975) Synthesis and coronary vasodilating activity of 2-substituted adenosines. Chem.Pharm.Bull. 23 759 PMID: 1182861


If you know of a relevant reference for CV 1808, please let us know.

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Keywords: CV 1808, CV 1808 supplier, Non-Selective, adenosines, A2, receptor, agonists, A2B, Receptors, A2A, CV1808, Adenosine, 1710, Tocris Bioscience

2 Citations for CV 1808

Citations are publications that use Tocris products. Selected citations for CV 1808 include:

Kan et al (2012) Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol 86 10338 PMID: 22787201

Baba et al (2018) Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation. J Bone Miner Res 33 1785 PMID: 29893999


Do you know of a great paper that uses CV 1808 from Tocris? Please let us know.

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