COR 170

Discontinued Product

COR 170 (Cat. No. 4756) has been withdrawn from sale for commercial reasons.
Description: Selective CB2 receptor inverse agonist
Chemical Name: N-(Adamant-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (1)

Biological Activity for COR 170

COR 170 is a selective inverse agonist of CB2 receptors (Ki values are 3.8 and >10,000 nM for CB2 and CB1, respectively).

Technical Data for COR 170

M. Wt 468.63
Formula C31H36N2O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 1048039-15-1
PubChem ID 25033736
InChI Key MSJISJDTJJYBFT-UHFFFAOYSA-N
Smiles O=C(C4=CN(CCCCC)C5=C(C=C(C6=CC=CC=C6)C=C5)C4=O)NC12CC(C3)CC(CC3C2)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for COR 170

References are publications that support the biological activity of the product.

Pasquini et al (2008) Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo. J.Med.Chem. 51 5075 PMID: 18680276

Contartese et al (2012) A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury. Pharmacol.Res. 66 555 PMID: 23036353

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Keywords: COR 170, COR 170 supplier, COR170, CB2, receptors, C2BR, inverse, agonists, selective, cannabinoids, Receptors, 4756, Tocris Bioscience

Citations for COR 170

Citations are publications that use Tocris products.

Currently there are no citations for COR 170.

Reviews for COR 170

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.