Clindamycin hydrochloride

Pricing Availability Delivery Time Qty
Cat.No. 4822 - Clindamycin hydrochloride | C18H33ClN2O5S.HCl | CAS No. 21462-39-5
Description: Antibiotic; inhibits protein synthesis
Chemical Name: Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride
Purity: ≥98% (HPLC)

Biological Activity

Lincosamide antibiotic. Inhibits protein synthesis by binding to the 50S ribosomal subunit and preventing early peptide chain elongation in bacteria.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

M. Wt 461.44
Formula C18H33ClN2O5S.HCl
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 21462-39-5
PubChem ID 16051951
Smiles CN1[C@H]([C@@](N[C@@]([H])([C@@]2([H])O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](Cl)C)=O)C[C@@H](CCC)C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 46.14 100

Preparing Stock Solutions

The following data is based on the product molecular weight 461.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.17 mL 10.84 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL
10 mM 0.22 mL 1.08 mL 2.17 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Champney and Tober (2000) Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr.Microbiol. 41 126 PMID: 10856379

Dhawan and Thadepalli (1982) Clindamycin: a review of fifteen years of experience. Rev.Infect.Dis. 4 1133 PMID: 6818656

If you know of a relevant reference for Clindamycin hydrochloride, please let us know.

View Related Products by Target

Keywords: Clindamycin hydrochloride, supplier, Lincosamide, antibiotics, bacterial, infections, inhibitors, inhibits, protein, synthesis, 50S, ribosomal, ribosome, bacteria, Antibiotics, Antibiotics, Tocris Bioscience

Citations for Clindamycin hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for Clindamycin hydrochloride. Do you know of a great paper that uses Clindamycin hydrochloride from Tocris? If so please let us know.

Commented out for usability testing


TODO: Add Reviews

Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for Clindamycin hydrochloride


TODO: Add Protocols