Home / Pharmacology / GPCRs / 7-TM Receptors / Adrenergic Receptors / Non-selective Adrenergic β Receptors / Non-selective Adrenergic β Receptor Agonists / Cimaterol

Cimaterol

Cat. No. 0435 2 Citations Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: β agonist
Chemical Name: 2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Reviews
Literature (4)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for Cimaterol

Cimaterol is a β-Adrenergic agonist.

Technical Data for Cimaterol

M. Wt 219.29
Formula C12H17N3O
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 54239-37-1
PubChem ID 2755
InChI Key BUXRLJCGHZZYNE-UHFFFAOYSA-N
Smiles CC(C)NCC(O)C1=CC=C(N)C(=C1)C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Cimaterol

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 21.93 100
DMSO 21.93 100

Preparing Stock Solutions for Cimaterol

The following data is based on the product molecular weight 219.29. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.56 mL 22.8 mL 45.6 mL
5 mM 0.91 mL 4.56 mL 9.12 mL
10 mM 0.46 mL 2.28 mL 4.56 mL
50 mM 0.09 mL 0.46 mL 0.91 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References for Cimaterol

References are publications that support the biological activity of the product.

Engelhardt (1984) Structure activity relationships in further series of amino-halogen substituted phenyl-aminoethanols. Arzneimittelforschung 11A 1625 PMID: 6152155

Strosberg and Pietri-Rouxel (1996) Function and regulation of the β3-adrenoceptor. TiPS 17 373 PMID: 8979772

Lafontan et al (1988) Mechanisms of actions of β-adrenergic agonists - lipomobilization and anabolism. Reprod.Nutr.Develop. 28 61

Merck Index 12 2336

If you know of a relevant reference for Cimaterol, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Non-selective Adrenergic β Receptor Agonists

Keywords: Cimaterol, Cimaterol supplier, β-adrenoceptor, beta-adrenoceptors, b-adrenoceptors, agonists, β-adrenergic, beta-adrenergic, b-adrenergic, Receptors, Non-Selective, Non-selective, Adrenergic, Beta, 0435, Tocris Bioscience

2 Citations for Cimaterol

Citations are publications that use Tocris products. Selected citations for Cimaterol include:

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther 329 350 PMID: 19144685

Mistry et al (2013) Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. J Med Chem 56 3852 PMID: 23614528

Do you know of a great paper that uses Cimaterol from Tocris? Please let us know.

Reviews for Cimaterol

There are currently no reviews for this product. Be the first to review Cimaterol and earn rewards!

Have you used Cimaterol?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure
GPCR Product Listing

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Cardiovascular Poster

Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.