Cimaterol

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Cat.No. 0435 - Cimaterol | C12H17N3O | CAS No. 54239-37-1
Description: β agonist
Chemical Name: 2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Reviews
Literature (4)

Biological Activity

β-Adrenergic agonist.

Technical Data

M. Wt 219.29
Formula C12H17N3O
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 54239-37-1
PubChem ID 2755
InChI Key BUXRLJCGHZZYNE-UHFFFAOYSA-N
Smiles CC(C)NCC(O)C1=CC=C(N)C(=C1)C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 21.93 100
DMSO 21.93 100

Preparing Stock Solutions

The following data is based on the product molecular weight 219.29. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.56 mL 22.8 mL 45.6 mL
5 mM 0.91 mL 4.56 mL 9.12 mL
10 mM 0.46 mL 2.28 mL 4.56 mL
50 mM 0.09 mL 0.46 mL 0.91 mL

Molarity Calculator

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References

References are publications that support the biological activity of the product.

Engelhardt (1984) Structure activity relationships in further series of amino-halogen substituted phenyl-aminoethanols. Arzneimittelforschung 11A 1625 PMID: 6152155

Strosberg and Pietri-Rouxel (1996) Function and regulation of the β3-adrenoceptor. TiPS 17 373 PMID: 8979772

Lafontan et al (1988) Mechanisms of actions of β-adrenergic agonists - lipomobilization and anabolism. Reprod.Nutr.Develop. 28 61

Merck Index 12 2336


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Keywords: Cimaterol, Cimaterol supplier, β-adrenoceptor, beta-adrenoceptors, b-adrenoceptors, agonists, β-adrenergic, beta-adrenergic, b-adrenergic, Receptors, Non-Selective, Non-selective, Adrenergic, Beta, 0435, Tocris Bioscience

2 Citations for Cimaterol

Citations are publications that use Tocris products. Selected citations for Cimaterol include:

Mistry et al (2013) Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. J Med Chem 56 3852 PMID: 23614528

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther 329 350 PMID: 19144685


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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