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Biological Activity for CID 1375606
CID 1375606 is a GPR27 agonist. Promotes recruitment of β-arrestin 2 to chimeric GPR27V2 and wild-type GPR27 in a firefly luciferase complementation assay (pEC50 values are 6.34 and 5.1, respectively).
Compound Libraries for CID 1375606
Technical Data for CID 1375606
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for CID 1375606
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for CID 1375606
The following data is based on the product molecular weight 385.24. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.6 mL||12.98 mL||25.96 mL|
|5 mM||0.52 mL||2.6 mL||5.19 mL|
|10 mM||0.26 mL||1.3 mL||2.6 mL|
|50 mM||0.05 mL||0.26 mL||0.52 mL|
References for CID 1375606
References are publications that support the biological activity of the product.
Dupuis et al (2017) Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment. Mol.Pharmacol. 91 595 PMID: 28314853
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Keywords: CID 1375606, CID 1375606 supplier, GPR27, agonists, agonism, SREB1, CID11375606, Orphan, 7-TM, Receptors, 6544, Tocris Bioscience
Citations for CID 1375606
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