CID 1375606

Pricing Availability   Qty
Description: GPR27 agonist
Chemical Name: 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide
Purity: ≥98% (HPLC)

Biological Activity for CID 1375606

CID 1375606 is a GPR27 agonist. Promotes recruitment of β-arrestin 2 to chimeric GPR27V2 and wild-type GPR27 in a firefly luciferase complementation assay (pEC50 values are 6.34 and 5.1, respectively).

Compound Libraries for CID 1375606

CID 1375606 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for CID 1375606

M. Wt 385.24
Formula C20H14Cl2N2O2
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 313493-80-0
PubChem ID 1375606
Smiles ClC1=CC(Cl)=C(C(NC2=CC=C(C(NC3=CC=CC=C3)=O)C=C2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CID 1375606

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 38.52 100

Preparing Stock Solutions for CID 1375606

The following data is based on the product molecular weight 385.24. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.6 mL 12.98 mL 25.96 mL
5 mM 0.52 mL 2.6 mL 5.19 mL
10 mM 0.26 mL 1.3 mL 2.6 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

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References for CID 1375606

References are publications that support the biological activity of the product.

Dupuis et al (2017) Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment. Mol.Pharmacol. 91 595 PMID: 28314853

If you know of a relevant reference for CID 1375606, please let us know.

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Citations for CID 1375606

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