Chlorphentermine hydrochloride

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Cat.No. 5573 - Chlorphentermine hydrochloride | C10H14ClN.HCl | CAS No. 151-06-4
Description: Serotonin transporter substrate; appetite suppressant
Chemical Name: 4-Chloro-α,α-dimethylbenzeneethanamine hydrochloride
Purity: ≥99% (HPLC)

Biological Activity

Serotonin transporter substrate (Ki = 338 nM). Appetite suppressant.

Technical Data

M. Wt 220.14
Formula C10H14ClN.HCl
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 151-06-4
PubChem ID 65477
Smiles ClC1=CC=C(CC(C)(N)C)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water and to 100 mM in DMSO

Preparing Stock Solutions

The following data is based on the product molecular weight 220.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.54 mL 22.71 mL 45.43 mL
5 mM 0.91 mL 4.54 mL 9.09 mL
10 mM 0.45 mL 2.27 mL 4.54 mL
50 mM 0.09 mL 0.45 mL 0.91 mL

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References are publications that support the products' biological activity.

Rothman et al (1999) Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation 100 869 PMID: 10458725

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Neurodegeneration Product Guide

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5-HT Receptors

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.