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Chemerin-9, Mouse is a chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Shimamura et al (2009) Identification of a stable chemerin analog with potent activity toward ChemR23. Peptides. 30 1529 PMID: 19540290
De Henau et al (2016) Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2. PLoS One. 11 PMID: 27716822
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Keywords: Chemerin-9, Mouse, Chemerin-9, Mouse supplier, chemerin, 9, chemokine, like, receptor, 1, 23, ChemR23, CMKLR1, agonists, agonism, 149, -, 157, mouse, Other, Chemokine, Receptors, 7117, Tocris Bioscience
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Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.