Chemerin-9, Human

Pricing Availability   Qty
Description: Potent CMKLR1 agonist; c-terminal peptide of full length human chemerin
Purity: ≥95% (HPLC)
Literature (1)

Biological Activity for Chemerin-9, Human

Chemerin-9, Human is a potent chemokine-like receptor 1 (CMKLR1; also known as chemerin receptor 23, ChemR23) agonist (EC50 = 7.1 nM at CMKLR expressed in CHO cells). Corresponds to C-terminal of full length human Chemerin, amino acids 149 - 157. Activates Gi/o signaling pathways in vitro; inhibits cAMP production and promotes phospholipase C production and Ca2+ mobilization.

Technical Data for Chemerin-9, Human

M. Wt 1063.18
Formula C54H66N10O13
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 676367-27-4
PubChem ID 11332190
Smiles O=C(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=C(C=C5)O)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Chemerin-9, Human

Solubility Soluble to 1 mg/ml in water

Product Datasheets for Chemerin-9, Human

Certificate of Analysis / Product Datasheet
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References for Chemerin-9, Human

References are publications that support the biological activity of the product.

Wittamer et al (2004) The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency. J.Med.Chem. 279 9956 PMID: 14701797

De Henau et al (2016) Signaling properties of chemerin receptors CMKLR1, GPR1 and CCRL2. PLoS One. 11 PMID: 27716822

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Keywords: Chemerin-9, Human, Chemerin-9, Human supplier, chemerin, 9, chemokine, like, receptor, 1, 23, ChemR23, CMKLR1, agonists, agonism, 149, -, 157, human, Other, Chemokine, Receptors, 7116, Tocris Bioscience

Citations for Chemerin-9, Human

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Literature in this Area

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