Cesium chloride

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Cat.No. 4739 - Cesium chloride | CsCl | CAS No. 7647-17-8
Description: Potassium channel blocker; neuroprotective
Reviews (1)

Biological Activity for Cesium chloride

Cesium chloride is a potassium channel blocker; inhibits the pacemaker current (If) and the hyperpolarization-activated cationic current (Ih). Prevents activation of caspase-3 and neuronal apoptosis in serum- and potassium-deprived cerebellar granule neurons by inactivating GSK-3β.

Technical Data for Cesium chloride

M. Wt 168.36
Formula CsCl
Storage Desiccate at RT
CAS Number 7647-17-8
PubChem ID 24293
Smiles [Cs]Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Cesium chloride

Solvent Max Conc. mg/mL Max Conc. mM
water 16.84 100

Preparing Stock Solutions for Cesium chloride

The following data is based on the product molecular weight 168.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.94 mL 29.7 mL 59.4 mL
5 mM 1.19 mL 5.94 mL 11.88 mL
10 mM 0.59 mL 2.97 mL 5.94 mL
50 mM 0.12 mL 0.59 mL 1.19 mL

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Product Datasheets for Cesium chloride

References for Cesium chloride

References are publications that support the biological activity of the product.

Zhong et al (2007) Cesium chloride protects cerebellar granule neurons from apoptosis induced by low potassium. Int.J.Dev.Neurosci. 25 359 PMID: 17804190

Sharma et al (2012) Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits. Neurol.Res. 34 291 PMID: 22450340

Wallick et al (1997) Effects of ionic channel antagonists barium, cesium, and UL-FS-49 on vagal slowing of atrial rate in dogs. Am.J.Physiol. 273 H2155 PMID: 9374748

If you know of a relevant reference for Cesium chloride, please let us know.

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Keywords: Cesium chloride, Cesium chloride supplier, Caesium, chloride, potassium, channel, blockers, If, Ih, currents, neuroprotective, apoptosis, CsCl, Non-selective, /, Other, Potassium, Channels, Apoptosis, HCN, 4739, Tocris Bioscience

Citations for Cesium chloride

Citations are publications that use Tocris products.

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Reviews for Cesium chloride

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CsCl was used to study cancerous neurons.
By Anonymous on 10/31/2018
Assay Type: In Vitro
Species: Human

CsCl was used to study cancerous neurons to understand their mechanism of change of pH. The product worked ideally on lab conditions and the paper was eventually published. Great affordable buy.

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