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Biological Activity for Cesium chloride
Cesium chloride is a potassium channel blocker; inhibits the pacemaker current (If) and the hyperpolarization-activated cationic current (Ih). Prevents activation of caspase-3 and neuronal apoptosis in serum- and potassium-deprived cerebellar granule neurons by inactivating GSK-3β.
Technical Data for Cesium chloride
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Cesium chloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Cesium chloride
The following data is based on the product molecular weight 168.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.94 mL||29.7 mL||59.4 mL|
|5 mM||1.19 mL||5.94 mL||11.88 mL|
|10 mM||0.59 mL||2.97 mL||5.94 mL|
|50 mM||0.12 mL||0.59 mL||1.19 mL|
References for Cesium chloride
References are publications that support the biological activity of the product.
Zhong et al (2007) Cesium chloride protects cerebellar granule neurons from apoptosis induced by low potassium. Int.J.Dev.Neurosci. 25 359 PMID: 17804190
Sharma et al (2012) Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits. Neurol.Res. 34 291 PMID: 22450340
Wallick et al (1997) Effects of ionic channel antagonists barium, cesium, and UL-FS-49 on vagal slowing of atrial rate in dogs. Am.J.Physiol. 273 H2155 PMID: 9374748
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Keywords: Cesium chloride, Cesium chloride supplier, Caesium, chloride, potassium, channel, blockers, If, Ih, currents, neuroprotective, apoptosis, CsCl, Non-selective, /, Other, Potassium, Channels, Apoptosis, HCN, 4739, Tocris Bioscience
Citations for Cesium chloride
Citations are publications that use Tocris products.
Currently there are no citations for Cesium chloride. Do you know of a great paper that uses Cesium chloride from Tocris? Please let us know.
Reviews for Cesium chloride
Average Rating: 5 (Based on 1 Review.)
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