Cesium chloride

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Cat.No. 4739 - Cesium chloride | CsCl | CAS No. 7647-17-8
Description: Potassium channel blocker; neuroprotective
Datasheet
Citations
Reviews
Literature

Biological Activity

Potassium channel blocker; inhibits the pacemaker current (If) and the hyperpolarization-activated cationic current (Ih). Prevents activation of caspase-3 and neuronal apoptosis in serum- and potassium-deprived cerebellar granule neurons by inactivating GSK-3β.

Technical Data

M. Wt 168.36
Formula CsCl
Storage Desiccate at RT
CAS Number 7647-17-8
PubChem ID 24293
InChI Key AIYUHDOJVYHVIT-UHFFFAOYSA-M
Smiles [Cs]Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 16.84 100

Preparing Stock Solutions

The following data is based on the product molecular weight 168.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.94 mL 29.7 mL 59.4 mL
5 mM 1.19 mL 5.94 mL 11.88 mL
10 mM 0.59 mL 2.97 mL 5.94 mL
50 mM 0.12 mL 0.59 mL 1.19 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Zhong et al (2007) Cesium chloride protects cerebellar granule neurons from apoptosis induced by low potassium. Int.J.Dev.Neurosci. 25 359 PMID: 17804190

Sharma et al (2012) Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits. Neurol.Res. 34 291 PMID: 22450340

Wallick et al (1997) Effects of ionic channel antagonists barium, cesium, and UL-FS-49 on vagal slowing of atrial rate in dogs. Am.J.Physiol. 273 H2155 PMID: 9374748


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Citations for Cesium chloride

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New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells