CCK Octapeptide, sulfated

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Description: C-terminal octapeptide of CCK
Alternative Names: Cholecystokinin Octapeptide, sulfated, CCK-8
Purity: ≥95% (HPLC)
Datasheet
Citations (8)
Reviews (1)
Literature (3)

Biological Activity for CCK Octapeptide, sulfated

CCK Octapeptide, sulfated is an endogenous C-terminal octapeptide of CCK found in the central nervous system and gastrointestinal tract.

Non-sulfated Peptide also available.

Technical Data for CCK Octapeptide, sulfated

M. Wt 1142.2
Formula C49H62N10O16S3
Sequence DYMGWMDF

(Modifications: Tyr-2 = SO3H, Phe-8 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 25126-32-3
PubChem ID 9833444
InChI Key IZTQOLKUZKXIRV-YRVFCXMDSA-N
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(OS(O)(=O)=O)C=C1)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CCK Octapeptide, sulfated

Solubility Soluble to 0.50 mg/ml in PBS (pH 7.4) with sonication

Product Datasheets for CCK Octapeptide, sulfated

Certificate of Analysis / Product Datasheet
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References for CCK Octapeptide, sulfated

References are publications that support the biological activity of the product.

Beinfel (1997) CCK biosynthesis and processing: recent progress and future challenges. Life Sci. 61 2359 PMID: 9399627

Gaw et al (1995) Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat. Br.J.Pharmacol. 115 660 PMID: 7582487

Heinemann et al (1995) Mediation by CCKB receptors of the CCK-evoked hyperaemia in rat gastric mucosa. Br.J.Pharmacol. 116 2274 PMID: 8564259

Wank (1998) G-protein-coupled receptors in gastrointestinal physiology. I. CCK receptors: an exemplary family. Am.J.Physiol. 274 G607 PMID: 9575840


If you know of a relevant reference for CCK Octapeptide, sulfated, please let us know.

View Related Products by Product Action

View all Non-selective CCK Agonists

Keywords: CCK Octapeptide, sulfated, CCK Octapeptide, sulfated supplier, C-terminal, octapeptide, CCK, Cholecystokinin, Non-Selective, Receptors, agonists, CCK-8, CCK8, Octapeptide,, sulfated, Non-selective, 1166, Tocris Bioscience

8 Citations for CCK Octapeptide, sulfated

Citations are publications that use Tocris products. Selected citations for CCK Octapeptide, sulfated include:

D'Agostino et al (2016) Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit. Regul Pept 5 PMID: 26974347

Hisadome et al (2011) CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs. Diabetes 60 2701 PMID: 21885869

Wu et al (2014) Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicol Sci 138 278 PMID: 24385417

Reidelberger et al (2014) Role of capsaicin-sensitive peripheral sensory neurons in anorexic responses to intravenous infusions of cholecystokinin, peptide YY-(3-36), and glucagon-like peptide-1 in rats. Am J Physiol Endocrinol Metab 307 E619 PMID: 25117406


Do you know of a great paper that uses CCK Octapeptide, sulfated from Tocris? Please let us know.

Reviews for CCK Octapeptide, sulfated

Average Rating: 4 (Based on 1 Review.)

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Applied to colon tissue.
By John Broad on 01/05/2018
Assay Type: In Vitro
Species: Human

1uM CCK contracts GI smooth muscle

review image

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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