Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 410.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.43 mL||12.17 mL||24.33 mL|
|5 mM||0.49 mL||2.43 mL||4.87 mL|
|10 mM||0.24 mL||1.22 mL||2.43 mL|
|50 mM||0.05 mL||0.24 mL||0.49 mL|
References are publications that support the products' biological activity.
Haeusler et al (1992) Pharmacological basis for antihypertensive therapy with a novel dopamine agonist Eur.Heart J. 13 129 PMID: 1356783
Rump et al (1993) Dopamine receptor modulation of noradrenaline release by carmoxirole in human cortical kidney slices. Eur.J.Clin.Pharmacol. 44 S47 PMID: 8097997
If you know of a relevant reference for Carmoxirole hydrochloride, please let us know.
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Keywords: Carmoxirole hydrochloride, supplier, Selective, peripherally, peripheral, D2-like, agonists, Dopamine, Non-Selective, Receptors, dopaminergic, EMD45609, EMD, 45609, Non-selective, Dopamine, Non-selective, Dopamine, Tocris Bioscience
2 Citations for Carmoxirole hydrochloride
Citations are publications that use Tocris products. Selected citations for Carmoxirole hydrochloride include:
Schlenker et al (2014) Hypothyroidism affects D2 receptor-mediated breathing without altering D2 receptor expression. Respir Physiol Neurobiol 193 29 PMID: 24434437
Schlenker and Schultz (2012) Hypothyroidism stimulates D2 receptor-mediated breathing in response to acute hypoxia and alters D2 receptors levels in carotid bodies and brain. Respir Physiol Neurobiol 180 69 PMID: 22051191
Do you know of a great paper that uses Carmoxirole hydrochloride from Tocris? If so please let us know.
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