Camstatin

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Cat.No. 0953 - Camstatin | Ala-Pro-Glu-Thr-Glu-Arg-Ala-Ala-Val-Ala-Ile-Gln-Ala-Gln-Phe-Arg-Lys-Phe-Gln-Lys-Lys-Lys-Ala-Gly-Ser-NH2 | CAS No. 1002295-95-5
Description: Calmodulin antagonist
Datasheet
Citations
Reviews

Biological Activity

An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.

Licensing Information

Sold with the permission of St. Jude Childrens Research Hospital

Technical Data

M. Wt 2760.19
Formula C122H203N39O34
Sequence APETERAAVAIQAQFRKFQKKKAGS

(Modifications: Ser-25 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 1002295-95-5
PubChem ID 90479747
InChI Key CZNWNBOOELGGSY-QCJADNLESA-N
Smiles [H]N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in water

References

References are publications that support the biological activity of the product.

Slemmon et al (1996) CamSTAT are peptide antagonists of calumodulin based upon a conserved structural motif in PEP-19, a neurogranin and neuromodulin J.Biol.Chem. 271 15911 PMID: 8663125


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Keywords: Camstatin, Camstatin supplier, Calmodulin, antagonists, Ca2+, Binding, Protein, modulators, Calcium, Signaling, Signalling, 0953, Tocris Bioscience

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