Camstatin

Pricing Availability Delivery Time Qty
Cat.No. 0953 - Camstatin | Ala-Pro-Glu-Thr-Glu-Arg-Ala-Ala-Val-Ala-Ile-Gln-Ala-Gln-Phe-Arg-Lys-Phe-Gln-Lys-Lys-Lys-Ala-Gly-Ser-NH2 | CAS No. 1002295-95-5
Description: Calmodulin antagonist
Datasheet
Citations

Biological Activity

An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.

Licensing Information

Sold with the permission of St. Jude Childrens Research Hospital

Technical Data

M. Wt 2760.19
Formula C122H203N39O34
Sequence APETERAAVAIQAQFRKFQKKKAGS

(Modifications: Ser-25 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 1002295-95-5
PubChem ID 90479747
InChI Key CZNWNBOOELGGSY-QCJADNLESA-N
Smiles [H]N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2760.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.36 mL 1.81 mL 3.62 mL
5 mM 0.07 mL 0.36 mL 0.72 mL
10 mM 0.04 mL 0.18 mL 0.36 mL
50 mM 0.01 mL 0.04 mL 0.07 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Slemmon et al (1996) Camstatins are peptide antagonists of calumodulin based upon a conserved structural motif in PEP-19, a neurogranin and neuromodulin J.Biol.Chem. 271 15911 PMID: 8663125


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Keywords: Camstatin, supplier, Calmodulin, antagonists, Ca2+, Binding, Protein, modulators, Calcium, Signaling, Signalling, Calcium, Binding, Protein, Modulators, Tocris Bioscience

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