Calcitonin (salmon)

Pricing Availability   Qty
Cat.No. 1159 - Calcitonin (salmon) | Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bridge: 1 - 7) | CAS No. 47931-85-1
Description: Affects bone formation and resorption
Datasheet
Citations
Reviews
Literature (3)

Biological Activity

Stimulates bone formation by osteoblasts and inhibits bone resorption.

Technical Data

M. Wt 3431.9
Formula C145H240N44O48S2
Sequence CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

(Modifications: Disulfide bridge between 1 - 7, Pro-32 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 47931-85-1
PubChem ID 16133812
InChI Key BBBFJLBPOGFECG-VJVYQDLKSA-N
Smiles [H]N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC1=O)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Poyner (1995) Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 16 424 PMID: 8578616

van Rossum et al (1997) Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors. Neurosci.Biobehav.Rev. 21 649 PMID: 9353797


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Keywords: Calcitonin (salmon), Calcitonin (salmon) supplier, bone, formation, resorption, AMY1, AMY2, AMY3, Amylin, CT, Calcitonin, agonist, and, Related, Receptors, 1159, Tocris Bioscience

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Literature in this Area

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