Calcitonin (human)

Pricing Availability   Qty
Cat.No. 6031 - Calcitonin (human) | Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2 | CAS No. 21215-62-3
Description: Endogenous calcitonin agonist; inhibits bone resorption
Literature (3)

Biological Activity for Calcitonin (human)

Calcitonin (human) is an endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.

Technical Data for Calcitonin (human)

M. Wt 3417.87
Formula C151H226N40O45S3

(Modifications: Pro-32 = C-terminal amide, Disulfide bridge between 1 - 7)

Storage Store at -20°C
CAS Number 21215-62-3
PubChem ID 122705992
Smiles [H]N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CNC1=O)[C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Calcitonin (human)

Solubility Soluble to 2 mg/ml in water

Product Datasheets for Calcitonin (human)

Certificate of Analysis / Product Datasheet
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References for Calcitonin (human)

References are publications that support the biological activity of the product.

Foster (1968) Calcitonin. A review of experimental and clinical investigations. Postgrad.Med.J. 44 411 PMID: 4871775

Bower and Hay (2016) Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development. Br.J.Pharmacol. 173 1883 PMID: 27061187

Lee et al (2016) Calcitonin and amylin receptor peptide interaction mechanisms. J.Biol.Chem. 291 16416 PMID: 27474777

If you know of a relevant reference for Calcitonin (human), please let us know.

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Keywords: Calcitonin (human), Calcitonin (human) supplier, endogenous, calcitonin, receptors, agonists, agonism, inhibits, bone, resorption, Calcitonin, and, Related, Receptors, 6031, Tocris Bioscience

Citations for Calcitonin (human)

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Literature in this Area

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