Calcitonin (human)

Pricing Availability   Qty
Cat.No. 6031 - Calcitonin (human) | Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2 | CAS No. 21215-62-3
Description: Endogenous calcitonin receptor agonist; inhibits bone resorption
Datasheet
Citations
Reviews
Literature

Biological Activity

Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.

Technical Data

M. Wt 3417.87
Formula C151H226N40O45S3
Sequence CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP

(Modifications: Pro-32 = C-terminal amide, Disulfide bridge between 1 - 7)

Storage Store at -20°C
CAS Number 21215-62-3
PubChem ID 122705992
InChI Key LCQDOKHKNORMTQ-JKQNMTHDSA-N
Smiles [H]N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CNC1=O)[C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 2 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Foster (1968) Calcitonin. A review of experimental and clinical investigations. Postgrad.Med.J. 44 411 PMID: 4871775

Bower and Hay (2016) Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development. Br.J.Pharmacol. 173 1883 PMID: 27061187

Lee et al (2016) Calcitonin and amylin receptor peptide interaction mechanisms. J.Biol.Chem. 291 16416 PMID: 27474777


If you know of a relevant reference for Calcitonin (human), please let us know.

View Related Products by Product Action

View all Calcitonin and Related Receptor Agonists

Keywords: Calcitonin (human), Calcitonin (human) supplier, endogenous, calcitonin, receptors, agonists, agonism, inhibits, bone, resorption, Calcitonin, and, Related, Receptors, 6031, Tocris Bioscience

Citations for Calcitonin (human)

Citations are publications that use Tocris products.

Currently there are no citations for Calcitonin (human). Do you know of a great paper that uses Calcitonin (human) from Tocris? Please let us know.

Reviews for Calcitonin (human)

There are currently no reviews for this product. Be the first to review Calcitonin (human) and earn rewards!

Have you used Calcitonin (human)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing
Peptides Involved in Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.