C14TKL-1

Pricing Availability Delivery Time Qty
Cat.No. 1939 - C14TKL-1 | Arg-His-Arg-Thr-Pro-Met-Phe-Tyr-Gly-Leu-Met-NH2
Description: Endogenous NK1 agonist
Alternative Names: Chromosome 14 tachykinin-like peptide 1
Datasheet
Citations

Biological Activity

Endogenous human tachykinin-like peptide and potent agonist for NK1 receptors (EC50 = 1 nM).

Technical Data

M. Wt 1406.7
Formula C63H98N20O13S2
Sequence RHRTPMFYGLM

(Modifications: Met-11 = C-terminal amide)

Storage Desiccate at -20°C
PubChem ID 90488729
InChI Key MMNLXHSWHPGRFE-MRQSSJIPSA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 1406.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.71 mL 3.55 mL 7.11 mL
5 mM 0.14 mL 0.71 mL 1.42 mL
10 mM 0.07 mL 0.36 mL 0.71 mL
50 mM 0.01 mL 0.07 mL 0.14 mL

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Jiang et al (2003) PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide. Mamm.Genome 14 341 PMID: 12856286


If you know of a relevant reference for C14TKL-1, please let us know.

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Keywords: Endogenous NK1 agonists Tachykinin Receptors Neurokinin Chromosome14 tachykinin-like peptide1 Chromosome 14 tachykinin-like peptide 1 NK1 Receptor Peptide

Citations for C14TKL-1

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