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C14TKL-1 is an endogenous human tachykinin-like peptide and potent agonist for NK1 receptors (EC50 = 1 nM).
(Modifications: Met-11 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Jiang et al (2003) PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide. Mamm.Genome 14 341 PMID: 12856286
Keywords: C14TKL-1, C14TKL-1 supplier, Endogenous, NK1, agonists, Tachykinin, Receptors, Neurokinin, Chromosome14, tachykinin-like, peptide1, Chromosome, 14, peptide, 1, Receptor, 1939, Tocris Bioscience
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.