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Submit ReviewBurimamide oxalate
Discontinued Product
1857 has been discontinued.
View all Histamine H<sub>2</sub> Receptors products.
Description: Mixed H2/H3 antagonist
Chemical Name: N-[4-(1H-Imidazol-4-yl)butyl]-N'-methylthiourea oxalate
Biological Activity for Burimamide oxalate
Histamine H3/H2 receptor antagonist (Ki values are 0.07, 7.8 and 290 μM for H3, H2 and H1 receptors respectively). Displays partial agonist activity in SK-N-MC cells. Produces antinociceptive effects following intraventricular administration (ED50 = 183 nmol/mouse in hot-plate test).
Technical Data for Burimamide oxalate
| M. Wt | 302.35 |
| Formula | C9H16N4S.C2H2O4 |
| Storage | Desiccate at +4°C |
| CAS Number | 163932-06-7 |
| Smiles | O=C(O)C(O)=O.S=C(NC)NCCCCC1=CN=CN1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Burimamide oxalate
References for Burimamide oxalate
References are publications that support the biological activity of the product.
Lamberti et al (1996) Investigation into the role of histamine receptors in rodent antinociception. Pharmacol.Biochem.Behav. 53 567 PMID: 8866956
Hough et al (2000) Antinociceptive activity of derivatives of improgran and burimamide. Pharmacol.Biochem.Behav. 65 61 PMID: 10638637
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Keywords: Burimamide oxalate, Burimamide oxalate supplier, Mixed, H2/H3, antagonists, H3, Receptors, Histamine, H2, histaminergic, 1857, Tocris Bioscience
Citations for Burimamide oxalate
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Histamine Receptors Scientific Review
Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.