Burimamide oxalate

Discontinued Product

Burimamide oxalate (Cat. No. 1857) has been withdrawn from sale for commercial reasons.
Cat.No. 1857 - Burimamide oxalate | C9H16N4S.C2H2O4 | CAS No. 163932-06-7
Description: Mixed H2/H3 antagonist
Chemical Name: N-[4-(1H-Imidazol-4-yl)butyl]-N'-methylthiourea oxalate
Datasheet
Citations
Reviews
Literature

Biological Activity

Histamine H3/H2 receptor antagonist (Ki values are 0.07, 7.8 and 290 μM for H3, H2 and H1 receptors respectively). Displays partial agonist activity in SK-N-MC cells. Produces antinociceptive effects following intraventricular administration (ED50 = 183 nmol/mouse in hot-plate test).

Technical Data

M. Wt 302.35
Formula C9H16N4S.C2H2O4
Storage Desiccate at +4°C
CAS Number 163932-06-7
Smiles O=C(O)C(O)=O.S=C(NC)NCCCCC1=CN=CN1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

References

References are publications that support the biological activity of the product.

Lamberti et al (1996) Investigation into the role of histamine receptors in rodent antinociception. Pharmacol.Biochem.Behav. 53 567 PMID: 8866956

Hough et al (2000) Antinociceptive activity of derivatives of improgran and burimamide. Pharmacol.Biochem.Behav. 65 61 PMID: 10638637

View Related Products by Product Action

View all Histamine H2 Receptor Antagonists

Keywords: Burimamide oxalate, Burimamide oxalate supplier, Mixed, H2/H3, antagonists, H3, Receptors, Histamine, H2, histaminergic, 1857, Tocris Bioscience

Citations for Burimamide oxalate

Citations are publications that use Tocris products.

Currently there are no citations for Burimamide oxalate.

Reviews for Burimamide oxalate

There are currently no reviews for this product. Be the first to review Burimamide oxalate and earn rewards!

Have you used Burimamide oxalate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Histamine Receptors

Histamine Receptors Scientific Review

Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.

Asthma

Asthma Poster

Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. This poster highlights key pathways and new therapies used to treat the condition, including those currently in clinical development.