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BU 226 hydrochloride
A high affinity ligand for I2 imidazoline sites (Ki = 2.7 nM) with very high selectivity (> 2000-fold) over α2-adrenoceptors (Ki = 6700 nM).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 233.7. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.28 mL||21.39 mL||42.79 mL|
|5 mM||0.86 mL||4.28 mL||8.56 mL|
|10 mM||0.43 mL||2.14 mL||4.28 mL|
|50 mM||0.09 mL||0.43 mL||0.86 mL|
References are publications that support the biological activity of the product.
Hudson et al (1999) Novel selective compounds for the investigation of imidazoline receptors. Ann.N.Y.Acad.Sci. 881 81 PMID: 10415900
Lione et al (1997) BU226: A selective ligand for rat brain imidazoline I2 sites. Soc.Neurosci.Abstr. 23 695.28
If you know of a relevant reference for BU 226 hydrochloride, please let us know.
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1 Citation for BU 226 hydrochloride
Citations are publications that use Tocris products. Selected citations for BU 226 hydrochloride include:
Gründemann et al (2002) Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells. Br J Pharmacol 137 910 PMID: 12411423
Do you know of a great paper that uses BU 226 hydrochloride from Tocris? Please let us know.
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Literature in this Area
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