Potent protein kinase C activator (KI = 2.75 nM). Attenuates phorbol 12-myristate 13-acetate (Cat. No. 1201) inhibition of GH4C1 pituitary cell proliferation in vitro.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in ethanol|
References are publications that support the biological activity of the product.
Mackanos et al (1991) Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation. J.Biol.Chem. 266 1120 PMID: 1904062
Wender et al (1988) Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C. Proc.Natl.Acad.Sci.U.S.A. 85 7197 PMID: 3174627
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