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Submit ReviewBRD 9757
Description: Potent and selective HDAC6 inhibitor
Chemical Name: N-Hydroxy-1-cyclopentene-1-carboxamide
Purity: ≥98% (HPLC)
Biological Activity for BRD 9757
BRD 9757 is a potent and selective HDAC6 inhibitor (IC50 = 30 nM). Displays selectivity for HDAC6 over Class I HDACS (>20-fold) and Class II HDACs (>400-fold).
Technical Data for BRD 9757
| M. Wt | 127.14 |
| Formula | C6H9NO2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1423058-85-8 |
| PubChem ID | 71655802 |
| InChI Key | RYYGSXXWQSXKRP-UHFFFAOYSA-N |
| Smiles | ONC(C1=CCCC1)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for BRD 9757
References for BRD 9757
References are publications that support the biological activity of the product.
Wagner et al (2013) Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif. J.Med.Chem. 56 1772 PMID: 23368884
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Keywords: BRD 9757, BRD 9757 supplier, BRD9757, potent, selective, HDAC6, inhibitors, inhibits, Class, II, HDACs, 6040, Tocris Bioscience
Citations for BRD 9757
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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