Neuropeptide with many biological effects including hormone release, stimulation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion.
(Modifications: X-1 = Glp, Met-13 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1619. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.62 mL||3.09 mL||6.18 mL|
|5 mM||0.12 mL||0.62 mL||1.24 mL|
|10 mM||0.06 mL||0.31 mL||0.62 mL|
|50 mM||0.01 mL||0.06 mL||0.12 mL|
References are publications that support the products' biological activity.
Battey and Wada (1991) Two distinct subtypes for mammalian bombesin-like peptides. TiNS 14 524 PMID: 1726343
McCoy and Avery (1990) Bombesin: potential integrative peptide for feeding and satiety. Peptides 11 595 PMID: 2199952
Tache et al (1988) Central nervous system action of bombesin to influence gastric secretion and ulceration. Ann.N.Y.Acad.Sci. 547 183 PMID: 3071217
If you know of a relevant reference for Bombesin, please let us know.
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2 Citations for Bombesin
Citations are publications that use Tocris products. Selected citations for Bombesin include:
Blais et al (2016) Gastrin-releasing peptide receptor mediates the excitation of preoptic GABAergic neurons by bombesin Neuroscience Letters 633 262 PMID: 27693662
Solorzano et al (2015) Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci 35 648 PMID: 25589759
Do you know of a great paper that uses Bombesin from Tocris? If so please let us know.
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Literature in this Area
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.