Bombesin

Pricing Availability   Qty
Cat.No. 1149 - Bombesin | Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 | CAS No. 31362-50-2
Description: Involved in gastrointestinal tract function
Datasheet
Citations (2)
Reviews
Literature

Biological Activity

Neuropeptide with many biological effects including hormone release, stimulation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion.

Technical Data

M. Wt 1619
Formula C71H110N24O18S
Sequence XQRLGNQWAVGHLM

(Modifications: X-1 = Glp, Met-13 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 31362-50-2
PubChem ID 16133800
InChI Key QXZBMSIDSOZZHK-DOPDSADYSA-N
Smiles [H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Battey and Wada (1991) Two distinct subtypes for mammalian bombesin-like peptides. TiNS 14 524 PMID: 1726343

McCoy and Avery (1990) Bombesin: potential integrative peptide for feeding and satiety. Peptides 11 595 PMID: 2199952

Tache et al (1988) Central nervous system action of bombesin to influence gastric secretion and ulceration. Ann.N.Y.Acad.Sci. 547 183 PMID: 3071217


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Keywords: Bombesin, Bombesin supplier, Involved, gastrointestinal, tract, function, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, agonists, 1149, Tocris Bioscience

2 Citations for Bombesin

Citations are publications that use Tocris products. Selected citations for Bombesin include:

Solorzano et al (2015) Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci 35 648 PMID: 25589759

Blais et al (2016) Gastrin-releasing peptide receptor mediates the excitation of preoptic GABAergic neurons by bombesin Neuroscience Letters 633 262 PMID: 27693662


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Literature in this Area

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