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Discontinued ProductBMS 605541 (Cat. No. 6069) has been withdrawn from sale for commercial reasons.
Biological Activity for BMS 605541
BMS 605541 is a potent ATP-competitive VEGFR-2 inhibitor (IC50 = 23 nM). Shows >10-fold selectivity for VEGFR-2 over VEGFR-1. Displays antitumor properties in human lung and colon tumor xenograft models. Orally bioavailable in rodents.
Technical Data for BMS 605541
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for BMS 605541
References are publications that support the biological activity of the product.
Borzilleri et al (2006) Discovery and evaluation of N-cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a selective and orally efficacious inhibitor of vascular endothelial growth factor receptor-2. J.Med.Chem 49 3766 PMID: 16789733
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Keywords: BMS 605541, BMS 605541 supplier, BMS605541, VEFGR-2, inhibitors, inhibits, antitumor, VEGFR, 6069, Tocris Bioscience
Citations for BMS 605541
Citations are publications that use Tocris products.
Currently there are no citations for BMS 605541.
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Literature in this Area
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