BIM 187

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Cat.No. 2716 - BIM 187 | D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-Leu-NH2 | CAS No. 137734-88-4
Description: Bombesin/GRP receptor agonist
Alternative Names: [D-Phe1,Leu8,9]litorin-NH2

Biological Activity

Bombesin/GRP receptor agonist that reduces food intake following i.p. administration.

Technical Data

M. Wt 1069.27
Formula C53H76N14O10

(Modifications: Phe-1 = D-Phe, Leu-9 = C-terminal amide)

Storage Store at -20°C
CAS Number 137734-88-4
PubChem ID 10819959
Smiles [H]N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1069.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.94 mL 4.68 mL 9.35 mL
5 mM 0.19 mL 0.94 mL 1.87 mL
10 mM 0.09 mL 0.47 mL 0.94 mL
50 mM 0.02 mL 0.09 mL 0.19 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Laferrere et al (1992) Effects of bombesin, of a new bombesin agonist (BIM187) and a new antagonist (BIM189) on food intake in rats, in relation to cholecystokinin. Eur.J.Pharmacol. 215 23 PMID: 1516647

If you know of a relevant reference for BIM 187, please let us know.

View Related Products by Target

Keywords: Bombesin/GRP receptor agonists GRP-Preferring Receptors Gastrin-Releasing Peptide-Preferring BB2 BIM187 [D-Phe1,Leu8,9]litorin-NH2 Bombesin Receptor Peptide

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