BIM 187

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Cat.No. 2716 - BIM 187 | D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-Leu-NH2 | CAS No. 137734-88-4
Description: Bombesin/GRP receptor agonist
Alternative Names: [D-Phe1,Leu8,9]litorin-NH2
Datasheet
Citations
Literature

Biological Activity

Bombesin/GRP receptor agonist that reduces food intake following i.p. administration.

Technical Data

M. Wt 1069.27
Formula C53H76N14O10
Sequence FQWAVGHLL

(Modifications: Phe-1 = D-Phe, Leu-9 = C-terminal amide)

Storage Store at -20°C
CAS Number 137734-88-4
PubChem ID 10819959
InChI Key HLAREJIMNCKKSS-XJZCOZNDSA-N
Smiles [H]N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1069.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.94 mL 4.68 mL 9.35 mL
5 mM 0.19 mL 0.94 mL 1.87 mL
10 mM 0.09 mL 0.47 mL 0.94 mL
50 mM 0.02 mL 0.09 mL 0.19 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Laferrere et al (1992) Effects of bombesin, of a new bombesin agonist (BIM187) and a new antagonist (BIM189) on food intake in rats, in relation to cholecystokinin. Eur.J.Pharmacol. 215 23 PMID: 1516647


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Keywords: BIM 187, supplier, Bombesin/GRP, receptor, agonists, GRP-Preferring, Receptors, Gastrin-Releasing, Peptide-Preferring, BB2, BIM187, [D-Phe1,Leu8,9]litorin-NH2, Bombesin, Receptors, Bombesin, Receptors, Tocris Bioscience

Citations for BIM 187

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