Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 2 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1746. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.57 mL||2.86 mL||5.73 mL|
|5 mM||0.11 mL||0.57 mL||1.15 mL|
|10 mM||0.06 mL||0.29 mL||0.57 mL|
|50 mM||0.01 mL||0.06 mL||0.11 mL|
References are publications that support the products' biological activity.
Gomes et al (2013) GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc.Natl.Acad.Sci.USA. 110 16211 PMID: 24043826
If you know of a relevant reference for BigLEN (rat), please let us know.
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Keywords: BigLEN (rat), supplier, agonists, agonism, GPR171, body, weight, neurite, outgrowth, GPR171, GPR171, Tocris Bioscience
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