Hepatocyte nuclear factor 4α (HNF4α) antagonist. Represses expression of known HNF4α target genes. Decreases HNF4α DNA binding. Exhibits cytotoxic activity in a range of tumor cell lines, including human hepatocellular carcinoma.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 331.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||15.09 mL||75.45 mL||150.9 mL|
|1 mM||3.02 mL||15.09 mL||30.18 mL|
|2 mM||1.51 mL||7.54 mL||15.09 mL|
|10 mM||0.3 mL||1.51 mL||3.02 mL|
References are publications that support the biological activity of the product.
Kiselyuk et al (2012) HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem.Biol. 19 806 PMID: 22840769
If you know of a relevant reference for BI 6015, please let us know.
Keywords: BI 6015, BI 6015 supplier, BI6015, Hepatocyte, nuclear, factor, 4, alpha, HNF4a, HNF4α, antagonists, DNA, binding, cancer, Other, Transcription, Factors, 4641, Tocris Bioscience
1 Citation for BI 6015
Citations are publications that use Tocris products. Selected citations for BI 6015 include:
Levy et al (2016) Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection Nature Chemical Biology 12 1037 PMID: 27723751
Do you know of a great paper that uses BI 6015 from Tocris? Please let us know.
Reviews for BI 6015
There are currently no reviews for this product. Be the first to review BI 6015 and earn rewards!
Have you used BI 6015?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Spring/Summer 2018)
Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Cell Metabolism
- Fluorescent Imaging
- Signal Transduction
- Stem Cells