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Biological Activity for BI 01383298
BI 01383298 is a potent and selective inhibitor of human SLC13A5 (Na+/citrate cotransporter; IC50 = 56 nM in HEK cells overexpressing hSLC13A5 and 24 nM in HepG2 cells with endogenous SLC13A5 expression). Displays >1000-fold selectivity over other family members.
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BI01383298 probe summary on the SGC website.
Compound Libraries for BI 01383298
Technical Data for BI 01383298
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for BI 01383298
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for BI 01383298
The following data is based on the product molecular weight 445.34. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||4.49 mL||22.45 mL||44.91 mL|
|2.5 mM||0.9 mL||4.49 mL||8.98 mL|
|5 mM||0.45 mL||2.25 mL||4.49 mL|
|25 mM||0.09 mL||0.45 mL||0.9 mL|
References for BI 01383298
References are publications that support the biological activity of the product.
Peters (2017) Flipping a citrate switch on liver cancer cells. J.Biol.Chem. 292 13902 PMID: 28821606
If you know of a relevant reference for BI 01383298, please let us know.
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Keywords: BI 01383298, BI 01383298 supplier, BI01383298, SLC13A5, inhibitors, inhibits, sodium, citrate, cotransporter, contransport, NaCT, NACT, INDY, Other, Ion, Pumps/Transporters, 6518, Tocris Bioscience
Citations for BI 01383298
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