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Discontinued ProductBazedoxifene acetate (Cat. No. 5263) has been withdrawn from sale for commercial reasons.
Biological Activity for Bazedoxifene acetate
Bazedoxifene acetate is a potent selective estrogen receptor modulator (SERM) (IC50 values are 26 and 99 nM for ERα and ERβ respectively). Inhibits 17β-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat. No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium.
Sold for research purposes under agreement from Pfizer Inc.
Compound Libraries for Bazedoxifene acetate
Technical Data for Bazedoxifene acetate
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Bazedoxifene acetate
References for Bazedoxifene acetate
References are publications that support the biological activity of the product.
Komm et al (2005) Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology 146 3999 PMID: 15961563
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