BA 1

Discontinued Product

BA 1 (Cat. No. 5600) has been withdrawn from sale for commercial reasons.
Description: Potent bombesin agonist
Citations (1)
Literature (1)

Biological Activity for BA 1

BA 1 is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell proliferation in vitro.

Technical Data for BA 1

M. Wt 1133.32
Formula C57H76N14O11

(Modifications: Tyr-1= D-Tyr, Ala-6 = β-Ala, X = Nle, Nle-9 = C-terminal amide)

Storage Store at -20°C
CAS Number 183241-31-8
PubChem ID 91826107
Smiles [H]N[C@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

View Related Products by Product Action

View all Bombesin Receptor Agonists

Keywords: BA 1, BA 1 supplier, BA1, bombesin, receptors, subtype3, BRS3, BB3, BB1, BB2, neuromedinB, NMBR, GRPR, gastrin-releasing, peptides, hormones, Bombesin, Receptors, 5600, Tocris Bioscience

1 Citation for BA 1

Citations are publications that use Tocris products. Selected citations for BA 1 include:

Acuña et al (2019) Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates. Cells 8 PMID: 31349736

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Peptides Involved in Appetite Modulation Scientific Review

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.