Orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (Ki = 75 μM, IC50 = 95 μM). Inhibits the production of PGD2 from PGH2 in vitro, with no effect on PGE2 or PGF2α production.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 397.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.03 mL||25.16 mL||50.31 mL|
|2.5 mM||1.01 mL||5.03 mL||10.06 mL|
|5 mM||0.5 mL||2.52 mL||5.03 mL|
|25 mM||0.1 mL||0.5 mL||1.01 mL|
References are publications that support the biological activity of the product.
Irikura et al (2009) Biochemical, functional and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. J.Biol.Chem. 284 7623 PMID: 19131342
If you know of a relevant reference for AT 56, please let us know.
View Related Products by Product Action
Keywords: AT 56, AT 56 supplier, AT56, L-PGDS, lipocalin-type, prostaglandin, PG, D, synthase, inhibitors, inhibits, Other, Synthases/Synthetases, 3531, Tocris Bioscience
1 Citation for AT 56
Citations are publications that use Tocris products. Selected citations for AT 56 include:
Jaurena et al (2015) Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport. Elife 6 7476 PMID: 26101153
Do you know of a great paper that uses AT 56 from Tocris? Please let us know.
Reviews for AT 56
There are currently no reviews for this product. Be the first to review AT 56 and earn rewards!
Have you used AT 56?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.