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Anti-TRPV1 blocking peptide
Discontinued ProductAnti-TRPV1 blocking peptide (Cat. No. 2335) has been withdrawn from sale for commercial reasons.
Synthetic peptide [C]-KPEDAEVFKDSMVPGEK) corresponding to C-terminal amino acids 822 to 838 of rat TRPV1 (Accession No. 35433), with a cysteine added at the N-terminus of the peptide for conjugation to KLH. Immunogen used for anti-TRPV1 (Cat. No. 2233).
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.