ANQ 11125

Pricing Availability   Qty
Cat.No. 5074 - ANQ 11125 | Phe-Val-Phe-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln | CAS No. 153966-48-4
Description: Selective motilin receptor antagonist
Datasheet
Citations
Reviews
Literature

Biological Activity

Selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.

Technical Data

M. Wt 1761.05
Formula C86H125N19O21
Sequence FVFIFTYGELQRLQ
Storage Store at -20°C
CAS Number 153966-48-4
PubChem ID 90489005
InChI Key YQKDYBMNXFOSLF-SDGXXZENSA-N
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

References

References are publications that support the biological activity of the product.

Depoortere et al (1995) Antagonistic properties of [Phe3,Leu13]porcine motilin. Eur.J.Pharmacol. 286 241 PMID: 8608785

Peeters et al (1994) The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochem.Biophys.Res.Commun. 198 411 PMID: 8297350


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Keywords: ANQ 11125, ANQ 11125 supplier, ANQ11125, Motilin, receptor, antagonists, motilides, Receptors, 5074, Tocris Bioscience

Citations for ANQ 11125

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Literature in this Area

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