ANQ 11125

Discontinued Product

ANQ 11125 (Cat. No. 5074) has been withdrawn from sale for commercial reasons.
Cat.No. 5074 - ANQ 11125 | Phe-Val-Phe-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln | CAS No. 153966-48-4
Description: Selective motilin receptor antagonist
Literature (3)

Biological Activity for ANQ 11125

ANQ 11125 is a selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.

Technical Data for ANQ 11125

M. Wt 1761.05
Formula C86H125N19O21
Storage Store at -20°C
CAS Number 153966-48-4
PubChem ID 90489005
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for ANQ 11125

References are publications that support the biological activity of the product.

Depoortere et al (1995) Antagonistic properties of [Phe3,Leu13]porcine motilin. Eur.J.Pharmacol. 286 241 PMID: 8608785

Peeters et al (1994) The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochem.Biophys.Res.Commun. 198 411 PMID: 8297350

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Keywords: ANQ 11125, ANQ 11125 supplier, ANQ11125, Motilin, receptor, antagonists, motilides, Receptors, 5074, Tocris Bioscience

Citations for ANQ 11125

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Currently there are no citations for ANQ 11125.

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