ANQ 11125

Pricing Availability Delivery Time Qty
Cat.No. 5074 - ANQ 11125 | Phe-Val-Phe-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln | CAS No. 153966-48-4
Description: Selective motilin receptor antagonist
Datasheet
Citations
Literature

Biological Activity

Selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.

Technical Data

M. Wt 1761.05
Formula C86H125N19O21
Sequence FVFIFTYGELQRLQ
Storage Store at -20°C
CAS Number 153966-48-4
PubChem ID 90489005
InChI Key YQKDYBMNXFOSLF-SDGXXZENSA-N
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 1761.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.57 mL 2.84 mL 5.68 mL
5 mM 0.11 mL 0.57 mL 1.14 mL
10 mM 0.06 mL 0.28 mL 0.57 mL
50 mM 0.01 mL 0.06 mL 0.11 mL

Molarity Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Depoortere et al (1995) Antagonistic properties of [Phe3,Leu13]porcine motilin. Eur.J.Pharmacol. 286 241 PMID: 8608785

Peeters et al (1994) The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochem.Biophys.Res.Commun. 198 411 PMID: 8297350


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Keywords: ANQ 11125, supplier, ANQ11125, Motilin, receptor, antagonists, motilides, Motilin, Receptors, Tocris Bioscience

Citations for ANQ 11125

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Literature in this Area

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Pathways for ANQ 11125

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