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Submit ReviewAniracetam
Discontinued Product
Aniracetam (Cat. No. 0867) has been withdrawn from sale for commercial reasons.
Description: Inhibits desensitization; AMPA > kainate
Chemical Name: 1-(4-Methoxybenzoyl)-2-pyrrolidinone
Purity: ≥99% (HPLC)
Biological Activity for Aniracetam
Aniracetam is a nootropic, with modulatory actions through allosteric potentiation of AMPA specific receptors, reduction of glutamate receptor desensitization and potentiation of metabotropic glutamate receptor activity. Anxiolytic following systemic administration.
Technical Data for Aniracetam
| M. Wt | 219.24 |
| Formula | C12H13NO3 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 72432-10-1 |
| PubChem ID | 2196 |
| InChI Key | ZXNRTKGTQJPIJK-UHFFFAOYSA-N |
| Smiles | COC1=CC=C(C=C1)C(=O)N1CCCC1=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Aniracetam
References for Aniracetam
References are publications that support the biological activity of the product.
Isaacson and Nicholl (1991) Aniracetam reduces glutamate receptor desensitisation and slows the decay of fast excitatory synaptic currents in the hippocampus. Proc.Natl.Acad.Sci.U.S.A. 88 10936 PMID: 1660156
Ito et al (1990) Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. J.Physiol. 424 553 PMID: 1975272
Nakamura and Kurasawa (2001) Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur.J.Pharmacol. 420 33 PMID: 11412837
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Keywords: Aniracetam, Aniracetam supplier, Desensitization, inhibitors, inhibits, AMPA, kainate, Glutamate, Receptors, iGluR, Ionotropic, allosteric, modulators, potentiators, 0867, Tocris Bioscience
1 Citation for Aniracetam
Citations are publications that use Tocris products. Selected citations for Aniracetam include:
Moldavan and Allen (2010) Retinohypothalamic tract synapses in the rat suprachiasmatic nucleus demonstrate short-term synaptic plasticity. J Neurophysiol 103 2390 PMID: 20220078
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